Introducing At-Home Injectable Ketamine Therapy

Medically reviewed by

Published on

January 13, 2025

Updated on

Ketamine therapy is one of the most effective, safe, and fast-acting mental health treatments on the market. Unfortunately, for most of its history, ketamine therapy hasn’t been accessible to Americans in need: treatment was only offered in a few clinics across the country that provided expensive and time-consuming IV ketamine infusions.

Mindbloom set out to transform Americans’ mental health by radically expanding access to ketamine therapy. By offering at-home treatment through telehealth, we’ve made ketamine therapy available to 86% of Americans and reduced the cost by 80%. Since 2019, Mindbloom has facilitated nearly 600,000 ketamine therapy sessions in 38 states.

The data show it’s working. After just four sessions, 89% of clients report improvements in symptoms, with many experiencing life-changing results. The outcomes in our two peer-reviewed studies (1, 2) are stronger than those shown for last-generation treatments for depression like SSRIs and psychotherapy.

The Next Step Forward: Mindbloom Injectables

Most clients achieve significant improvements in depression, anxiety, and PTSD with our sublingual ketamine tablets. However, when we examined our data, we saw an opportunity to improve client experiences and outcomes by offering alternative routes of administration.

To provide our clients with the best possible outcomes and more treatment options, our clinical team began developing new protocols to offer ketamine via subcutaneous injection (Mindbloom Injectables), which delivers the medicine just under the skin of the abdomen using a tiny needle.

Before launching Mindbloom Injectables, we undertook a year-long pilot to confirm this would deliver an effective, safe, and comfortable experience for our clients, under the supervision and input of an expert Medical Review Board.

What makes injectable ketamine therapy exceptional?

Reliable results: Precise dosing and greater session consistency

Easy administration: 81% of clients report preferring injectable ketamine over sublingual tablets, citing greater comfort and a sense of control during their sessions.

Accessibility: The comfort and convenience of at-home treatment that is up to 90% more affordable than IV infusions—no need for driving, clinic visits, or added hassle.

At Mindbloom, we understand that ketamine therapy is about more than just the medicine. Mindbloom Injectables are part of a comprehensive program that includes 1:1 coaching, integration content, and a supportive community to help you achieve meaningful, lasting progress.

Interested in learning more?

If you’re curious about how injectable ketamine therapy works and whether it’s a good fit for you download our free White Paper.

‍

Mindbloom Editorial Team

Mindbloom is a leader in psychedelic therapy, transforming lives to transform the world. Our editorial team shares the latest Mindbloom news, and collaborates with Mindbloom clients to help share their stories with the world.

This article is for informational purposes only and is not intended to be a substitute for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. If you are in a life-threatening situation, call the National Suicide Prevention Line at +1 (800) 273-8255, call 911, or go to the nearest emergency room.

Safety Information

Important FDA Safety Information

Ketamine is not FDA-approved for the treatment of depression or anxiety. Learn more about off-label uses here.

Side effects of ketamine treatment may include: altered sense of time, anxiety, blurred vision, diminished ability to see/hear/feel, dry mouth, elevated blood pressure or heart rate, elevated intraocular or intracranial pressure, excitability, loss of appetite, mental confusion, nausea/vomiting, nystagmus (rapid eye movements), restlessness, slurred speech, synesthesia (a mingling of the senses).

Do not proceed with ketamine treatment if any of the following apply to you:

Allergic to ketamine
Symptoms of psychosis or mania
Uncontrolled high blood pressure
CHF or other serious heart problem
Severe breathing problem
History of elevated intraocular or intracranial pressure
History of hyperthyroidism
Other serious medical illness
Pregnant, nursing, or trying to become pregnant

Ketamine has been reported to produce issues including, but not limited to, those listed below. However, lasting adverse side-effects are rare when medical protocols are carefully followed.

While ketamine has not been shown to be physically addictive, it has been shown to cause moderate psychological dependency in some recreational users.

In rare cases, frequent, heavy users have reported increased frequency of urination, urinary incontinence, pain urinating, passing blood in the urine, or reduced bladder size
Ketamine may worsen problems in people with schizophrenia, severe personality disorders, or other serious mental disorders.
Users with a personal or family history of psychosis should be cautious using any psychoactive substance, including ketamine, and discuss potential risks with your MindBloom^® clinician before proceeding with treatment.
The dissociative effects of ketamine may increase patient vulnerability and the risk of accidents.

To promote positive outcomes and ensure safety, follow these ketamine treatment guidelines:

Do not operate a vehicle (e.g., car, motorcycle, bicycle) or heavy machinery following treatment until you’ve had a full night of sleep
Refrain from taking benzodiazepines or stimulants for 24 hours prior to treatment
Continue to take antihypertensive medication as prescribed
Avoid hangovers or alcohol intake
Refrain from consuming solid foods within 3 hours prior to treatment and liquids within 1 hour prior to treatment
Ketamine treatment should never be conducted without a monitor present to ensure your safety